ホメオパシーの科学的根拠(その13)

出典:日本ホメオパシー医学協会

アリゾナ大学薬学部 Iris R. Bell 医学博士による ホメオパシーのエビデンス集
http://www.jphma.org/fukyu/overseas_100124_evidence.html

ホメオパシーの有効性を実証した100以上の論文(エビデンス)がリストアップされています。

※引用元アドレス
http://www.homeopathic.org/content/homeopathy-research-evidence-base-references

■Aickin M. The end of biomedical journals: there is madness in their methods. Journal of Alternative & Complementary Medicine 2005; 11 (5):755-7.

■Aickin M. Participant-centered analysis in complementary and alternative medicine comparative trials. J Alternative & Complementary Medicine 2003; 9 (6):949-57.

■Aickin M. Separation tests for early-phase CAM comparative trials. Evidence-Based Integrative Medicine 2004; 1 (4):225-31.

■Becker-Witt C, Weibhuhn T.E.R., Ludtke, R., Willich, S.N. Quality assessment of physical research in homeopathy. Journal of Alternative & Complementary Medicine 2003; 9 (1):113-32.

■Bell IR. All evidence is equal, but some evidence is more equal than others: can logic prevail over emotion in the homeopathy debate? J Altern Complement Med. 2005; 11 (5):763-9.

■Bell IR. Evidence-based homeopathy: empirical questions and methodological considerations for homeopathic clinical research. American Journal of Homeopathic Medicine 2003; 96 (1):17-31.

■Bell IR, Baldwin CM, Schwartz GE. Translating a nonlinear systems theory model for homeopathy into empirical tests. Alternative Therapies in Health & Medicine. 2002a; 8 (3):58-66.

■Bell IR, Caspi O, Schwartz GE et al. Integrative medicine and systemic outcomes research: issues in the emergence of a new model for primary health care. Archives of Internal Medicine. 2002b; 162 (2):133-40.

■Bell IR, Koithan M. Models for the study of whole systems. Integrative Cancer Therapies 2006; 5 (4):293-307.

■Bell IR, Lewis DA, 2nd, Brooks AJ et al. Individual differences in response to randomly assigned active individualized homeopathic and placebo treatment in fibromyalgia: implications of a double-blinded optional crossover design. Journal of Alternative & Complementary Medicine 2004a; 10 (2):269-83.

■Bell IR, Lewis DA, 2nd, Brooks AJ et al. Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo. Rheumatology 2004b; 43 (5):577-82.

■Bell IR, Lewis DA, 2nd, Lewis SE et al. EEG alpha sensitization in individualized homeopathic treatment of fibromyalgia. International Journal of Neuroscience 2004c; 114 (9):1195-220.

■Bell IR, Lewis DAI, Schwartz GE et al. Electroencephalographic cordance patterns distinguish exceptional clinical responders with fibromyalgia to individualized homeopathic medicines. J Alternative & Complementary Medicine 2004d; 10 (2):285-99.

■Bell IR, Walsh, M., Russek, L.G.S., Schwartz, G.E.R. Proposed applications of conventional research concepts and tools to homeopathic clinical research. Journal of the American Institute of Homeopathy 1999; 92 (3):111-28.

■Bellavite P. Complexity science and homeopathy: a synthetic overview. Homeopathy: the Journal of the Faculty of Homeopathy. 2003; 92 (4):203-12.

■Bellavite P, Conforti A, Pontarollo F et al. Immunology and homeopathy. 2. Cells of the immune system and inflammation. Evid Based Complement Alternat Med 2006; 3 (1):13-24.

■Bellavite P, Signorini, A. The Emerging Science of Homeopathy. Complexity, Biodynamics, and Nanopharmacology. 2nd ed. Berkeley: North Atlantic Books; 2002. 408 pp. p.

■Bertani S, Lussignoli S, Andrioli G et al. Dual effects of a homeopathic mineral complex on carrageenan-induced oedema in rats. British Homoeopathic Journal 1999; 88 (3):101-5.

■Betti L, Lazzarato L, Trebbi G et al. Effects of homeopathic arsenic on tobacco plant resistance to tobacco mosaic virus. Theoretical suggestions about system variability, based on a large experimental data set. Homeopathy 2003; 92 (4):195-202.

■Bikker AP, Mercer SW, Reilly D. A pilot prospective study on the consultation and relational empathy, patient enablement, and health changes over 12 months in patients going to the Glasgow Homoeopathic Hospital. J Altern Complement Med. 2005; 11 (4):591-600.

■Biswas SJ, Pathak S, Bhattacharjee N et al. Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-dimethylaminoazobenzene-induced hepatocarcinogenesis in mice. J Altern Complement Med 2005; 11 (5):839-54.

■Bootzin RR, Bailey ET. Understanding placebo, nocebo, and iatrogenic treatment effects. J Clin Psychology 2005; 61 (7):871-80.

■Brizzi M, Lazzarato L, Nani D et al. A biostatistical insight into the As(2)O(3) high dilution effects on the rate and variability of wheat seedling growth. Forsch Komplementarmed Klass Naturheilkd 2005; 12 (5):277-83.

■Caspi O, Bell IR. One size does not fit all: aptitude-treatment interaction (ATI) as a conceptual framework for outcome research. Part I. What is ATI research? Journal of Alternative & Complementary Medicine 2004a; 10 (3):580-6.

■Caspi O, Bell IR. One size does not fit all: aptitude-treatment interaction (ATI) as a conceptual framework for outcome research. Part II. Research designs and their application. . Journal of Alternative and Complementary Medicine. 2004b; 10 (4):698-705.

■Caulfield T, DeBow S. A systematic review of how homeopathy is represented in conventional and CAM peer reviewed journals. BMC Complement Altern Med. 2005; 5 (1):12.

■Chaplin MF. The Memory of Water: an overview. Homeopathy. 2007; 96 (3):143-50
Chapman EH, Weintraub RJ, Milburn MA et al. Homeopathic treatment of mild traumatic brain injury: A randomized, double-blind, placebo-controlled clinical trial. Journal of Head Trauma Rehabilitation 1999; 14 (6):521-42.

■Coffey DS. Self-organization, complexity, and chaos: the new biology for medicine. Nature Medicine. 1998; 4 (8):882-5.

■Conforti A, Bellavite P, Bertani S et al. Rat models of acute inflammation: a randomized controlled study on the effects of homeopathic remedies. BMC Complement Altern Med 2007; 7:1.

■Dean ME, Coulter MK, Fisher P et al. Reporting data on homeopathic treatments (RedHot): a supplement to CONSORT. J Altern Complement Med 2007; 13 (1):19-23.

■Eizayaga FX, Aguejouf O, Belon P et al. Platelet aggregation in portal hypertension and its modification by ultra-low doses of aspirin. Pathophysiol Haemost Thromb 2005; 34 (1):29-34.

■Eizayaga FX, Aguejouf O, Desplat V et al. Modifications produced by indomethacin and L-NAME in the effect of ultralow-dose aspirin on platelet activity in portal hypertension. Pathophysiol Haemost Thromb 2006; 35 (5):357-63.

■Elia V, Napoli E, Germano R. The ‘Memory of Water’: an almost deciphered enigma. Dissipative structures in extremely dilute aqueous solutions. Homeopathy. 2007; 96 (3):163-9.

■Elia V, Niccoli, M. New physico-chemical properties of extremely diluted aqueous solutions. Journal of Thermal Analysis and Calorimetry 2004; 75:815-36.

■Elia V, Niccoli, M. Thermodynamics of extremely diluted aqueous solutions. Annals of the New York Academy of Sciences 1999; 879:241-8.

■Endler PC, Pongratz W, Kastberger G et al. The effect of highly diluted agitated thyroxine on the climbing activity of frogs. Vet Hum Toxicol 1994; 36 (1):56-9.

■Endler PC, Pongratz W, Smith CW et al. Non-molecular information transfer from thyroxine to frogs with regard to homeopathic toxicology. Veterinary & Human Toxicology. 1995; 37 (3):259-60.

■Endler PC, Pongratz, W., van Wijk, R., Wiegant, F.A.C., Waltl, K., Gehrer, M., Hilgers, H. A zoological example on ultra high dilution research. Energetic coupling between the dilution and the organism in a model of amphibia. In: PC Endler, Schulte, J., editor, translator and editor Ultra High Dilution. Dordrecht, The Netherlands: Kluwer Academic Publishers;
1994; p. 39-68.

■Fisher P. Homeopathy and The Lancet. Evid Based Complement Alternat Med 2006; 3 (1):145-7.

■Frei H, Everts R, von Ammon K et al. Randomised controlled trials of homeopathy in hyperactive children: treatment procedure leads to an unconventional study design Experience with open-label homeopathic treatment preceding the Swiss ADHD placebo controlled, randomised, double-blind, cross-over trial. Homeopathy 2007; 96 (1):35-41.

■Frei H, Everts R, von Ammon K, Kaufmann F, Walther D, Hsu-Schmitz SF, Collenberg M, Fuhrer K, Hassink R, Steinlin M, Thurneysen A. Homeopathic treatment of children with attention deficit hyperactivity disorder: a randomised, double blind, placebo controlled crossover trial. Eur J Pediatr. 2005; 164 (12):758-67.

■Frei H, Thurneysen A, von Ammon K. Methodological difficulties in homeopathic treatment of children with ADD/ADHD. J Altern Complement Med 2006a; 12 (2):104; author reply

■Frei H, Thurneysen A. Treatment for hyperactive children: homeopathy and methylphenidate compared in a family setting. British Homoeopathic Journal 2001; 90 (4):183-8.

■Frei H, von Ammon K, Thurneysen A. Treatment of hyperactive children: increased efficiency through modifications of homeopathic diagnostic procedure. Homeopathy. 2006b; 95 (3):163-70.

■Frenkel M, Hermoni D. Effects of homeopathic intervention on medication consumption in atopic and allergic disorders. Altern Ther Health Med 2002; 8 (1):76-9.
Goldstein MS, Glik, D. Use of and satisfaction with homeopathy in a patient population.

■Alternative Therapies in Health & Medicine 1998; 4 (2):60-5.
Guthlin C, Lange O, Walach H. Measuring the effects of acupuncture and homoeopathy in general practice: an uncontrolled prospective documentation approach. BMC Public Health 2004; 4 (1):4.

■Haidvogl M, Riley DS, Heger M, Brien S, Jong M, Fischer M, Lewith GT, Jansen G, Thurneysen AE. Homeopathic and conventional treatment for acute respiratory and ear complaints: a comparative study on outcome in the primary care setting. BMC Complement Altern Med. 2007; 2;7:7.

■Honda K, Jacobson JS. Use of complementary and alternative medicine among United States adults: the influences of personality, coping strategies, and social support. Preventive Medicine 2005; 40 (1):46-53.

■Hyland ME, Lewith GT. Oscillatory effects in a homeopathic clinical trial: an explanation using complexity theory, and implications for clinical practice. Homeopathy 2002; 91 (3):145-9.

■Jacobs J, Jimenez LM, Gloyd SS et al. Treatment of acute childhood diarrhea with homeopathic medicine: a randomized clinical trial in Nicaragua. Pediatrics. 1994; 93 (5):719-25.

■Jacobs J, Jimenez LM, Malthouse S et al. Homeopathic treatment of acute childhood diarrhea: results from a clinical trial in Nepal. Journal of Alternative & Complementary Medicine 2000; 6 (2):131-9.

■Jacobs J, Jonas WB, Jimenez-Perez M et al. Homeopathy for childhood diarrhea: combined results and metaanalysis from three randomized, controlled clinical trials. Pediatric Infectious Disease Journal 2003; 22 (3):229-34.

■Jacobs J, Williams AL, Girard C et al. Homeopathy for attention-deficit/hyperactivity disorder: a pilot randomized-controlled trial. J Altern Complement Med 2005; 11 (5):799-806.

■Jonas W, Lin Y, Tortella F. Neuroprotection from glutamate toxicity with ultra-low dose glutamate. Neuroreport 2001; 12 (2):335-9.

■Jonas W, Lin, Y., Williams, A., Tortella, F., Tuma, R. Treatment of experimental stroke with low-dose glutamate and homeopathic Arnica montana. Perfusion 1999a; 12:452-62.

■Jonas WB. Do homeopathic nosodes protect against infection? An experimental test. Alternative Therapies in Health & Medicine 1999b; 5 (5):36-40.

■Jonas WB. The future of hormesis: what is the clinical relevance to hormesis? Critical Reviews in Toxicology. 2001; 31 (4-5):655-8.

■Jonas WB, Kaptchuk TJ, Linde K. A critical overview of homeopathy. Annals of Internal Medicine. 2003; 138 (5):393-9.

■Jutte R, Riley D. A review of the use and role of low potencies in homeopathy. Complement Ther Med 2005; 13 (4):291-6.

■Kundu SN, Mitra K, Khuda Bukhsh AR. Efficacy of a potentized homeopathic drug (Arsenicum-Aalbum-30) in reducing cytotoxic effects produced by arsenic trioxide in mice: IV. Pathological changes, protein profiles, and content of DNA and RNA. Complementary Therapies in Medicine 2000; 8 (3):157-65.

■Lamont J. Homeopathic treatment of attention deficit hyperactivity disorder. A controlled study. British Homoeopathic Journal 1997; 86:196-200.

■Langman MJS. Homeopathy trials: reason for good ones but are they warranted? Lancet 1997; 350:825.

■Lewith GT, Watkins AD, Hyland ME et al. Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: double blind randomised controlled clinical trial. BMJ 2002; 324 (7336):520-3

■Linde K, Clausius N, Ramirez G et al. Are the clinical effects of homeopathy placebo effects? A meta-analysis of placebo-controlled trials. Lancet 1997; 350:834-43.

■Linde K, Jonas WB, Melchart D et al. The methodological quality of randomized controlled trials of homeopathy, herbal medicines and acupuncture. International Journal of Epidemiology 2001; 30 (3):526-31.

■Lussignoli S, Bertani S, Metelmann H et al. Effect of Traumeel S, a homeopathic formulation, on blood-induced inflammation in rats. Complementary Therapies in Medicine 1999; 7 (4):225-30.

■Mallick P, Mallick JC, Guha B et al. Ameliorating effect of microdoses of a potentized homeopathic drug, Arsenicum Album, on arsenic-induced toxicity in mice. BMC Complement Altern Med 2003; 3:7.

■Marotta D, Marini A, Banaudha K et al. Non-linear effects of cycloheximide in glutamate-treated cultured rat cerebellar neurons. Neurotoxicology. 2002; 23 (3):307-12.

■Marotta D, Marini, A, Banaudha, K., Maharaj, S., Jonas, W.B. Nonlinear effects of glutamate and KCl on glutamate toxicity in cultured rat cerebellar neurons. International Journal of Neuroscience 2003; 113:45-56.

■Mathie RT. The research evidence base for homeopathy: a fresh assessment of the literature. Homeopathy: the Journal of the Faculty of Homeopathy. 2003; 92:84-91.

■Mathie RT, Hansen L, Elliott MF et al. Outcomes from homeopathic prescribing in veterinary practice: a prospective, research-targeted, pilot study. Homeopathy 2007; 96 (1):27-34.

■Milgrom LR. Are randomized controlled trials (RCTs) redundant for testing the efficacy of homeopathy? A critique of RCT methodology based on entanglement theory. J Altern Complement Med 2005; 11 (5):831-8.

■Neville-Smith R. Community hospital homeopathy clinic: audit of the first 12 months activity. British Homoeopathic Journal 1999; 88 (1):20-3.

■Oberbaum M, Singer SR, Vithoulkas G. The colour of the homeopathic improvement: the multidimensional nature of the response to homeopathic therapy. Homeopathy. 2005; 94 (3):196-9.

■Oberbaum M, Vithoulkas G, Van Haselen R. Clinical trials of classical homeopathy: reflections on appropriate research designs. Journal of Alternative & Complementary Medicine 2003; 9 (1):105-11.

■Oberbaum M, Yaniv I, Ben-Gal Y et al. A randomized, controlled clinical trial of the homeopathic medication TRAUMEEL S in the treatment of chemotherapy-induced stomatitis in children undergoing stem cell transplantation. Cancer 2001; 92 (3):684-90.

■Rao ML, Roy R, Bell IR et al. The defining role of structure (including epitaxy) in the plausibility of homeopathy. Homeopathy 2007; 96 (3):175-82.

■Reilly D, Taylor, M.A., Beattie, N.G.M., Campbell, J.H., McSharry, C., Aitchison, T.C., Carter, R., Stevenson, R.D. Is evidence for homeopathy reproducible? Lancet 1994; 344:1601-6.

■Relton C, Weatherley-J
ones E. Homeopathy service in a National Health Service community menopause clinic: audit of clinical outcomes. Journal of the British Menopause Society. 2005; 11 (2):72-3.

■Rey L. Thermoluminescence of ultra-high dilutions of lithium chloride and sodium chloride. Physica A: Statistical mechanics and its applications. 2003; 323:67-74.

■Riley D, Fischer M, Singh B et al. Homeopathy and conventional medicine: an outcomes study comparing effectiveness in a primary care setting. Journal of Alternative & Complementary Medicine 2001; 7 (2):149-59.

■Robinson N, Donaldson J, Watt H. Auditing outcomes and costs of integrated complementary medicine provision–the importance of length of follow up. Complement

■Ther Clin Pract 2006; 12 (4):249-57.
Roy R, Tiller W, Bell IR et al. The Structure of Liquid Water: Novel Insights from Materials Research and Potential Relevance to Homeopathy. Materials Research Innovation 2005; 9 (4):557-608.

■Ruiz-Vega G, Perez-Ordaz L, Proa-Flores P et al. An evaluation of Coffea cruda effect on rats. British Homoeopathic Journal 2000; 89 (3):122-6.

■Ruiz-Vega G, Perez-Ordaz, L., Leon-Hueramo, O., Cruz-Vazquez, E., Sanchez-Diaz, N. Comparative effect of Coffea cruda potencies on rats. Homeopathy 2002; 91:80-4.

■Ruiz-Vega G, Poitevin B, Perez-Ordaz L. Histamine at high dilution reduces spectral density in delta band in sleeping rats. Homeopathy 2005; 94 (2):86-91.

■Ruiz G, Torres JL, Michel O et al. Homeopathic effect on heart rate variability. British Homoeopathic Journal 1999; 88 (3):106-11.

■Ruiz G, Torres, J.L. Homeopathic effect on the sleep pattern of rats. British Homoeopathic Journal 1997; 86:201-6.

■Sevar R. Audit of outcome in 455 consecutive patients treated with homeopathic medicines. Homeopathy. 2005; 94 (4):215-21.

■Sevar R. Audit of outcome in 829 consecutive patients treated with homeopathic medicines. British Homoeopathic Journal 2000; 89 (4):178-87.

■Sukul A, Sarkar P, Sinhababu SP et al. Altered solution structure of alcoholic medium of potentized Nux vomica underlies its antialcoholic effect. British Homoeopathic Journal 2000; 89 (2):73-7.

■Sukul A, Sinhabau SP, Sukul NC. Reduction of alcohol induced sleep time in albino mice by potentized Nux vomica prepared with 90% ethanol. British Homoeopathic Journal 1999; 88 (2):58-61.

■Sukul NC, Bala, S.K., Bhattacharyya, B. Prolonged cataleptogenic effects of potentized homoeopathic drugs. Psychopharmacology 1986; 89:338-9.

■Sukul NC, De A, Sukul A et al. Potentized Mercuric chloride and Mercuric iodide enhance alpha-amylase activity in vitro. Homeopathy: the Journal of the Faculty of
Homeopathy. 2002; 91 (4):217-20.

■Sukul NC, Ghosh S, Sinhababu SP. Reduction in the number of infective Trichinella spiralis larvae in mice by use of homeopathic drugs. Forschende Komplementarmedizin und Klassische Naturheilkunde 2005; 12 (4):202-5.

■Sukul NC, Ghosh S, Sinhababu SP et al. Strychnos nux-vomica extract and its ultra-high dilution reduce voluntary ethanol intake in rats. Journal of Alternative & Complementary Medicine 2001; 7 (2):187-93.

■Szeto AL, Rollwagen F, Jonas WB. Rapid induction of protective tolerance to potential terrorist agents: a systematic review of low- and ultra-low dose research. [Review] [19 refs]. Homeopathy: the Journal of the Faculty of Homeopathy 2004; 93 (4):173-8.
Thompson E, Barron S, Spence D. A preliminary audit investigating remedy reactions including adverse events in routine homeopathic practice. Homeopathy: Journal of the Faculty of Homeopathy. 2004; 93 (4):203-9.

■Thompson EA, Oxon, B.A., Montgomery, A., Douglas, D., Reilly, D. A Pilot, Randomized, Double-Blinded, Placebo-Controlled Trial of Individualized Homeopathy for Symptoms of Estrogen Withdrawal in Breast-Cancer Survivors. Journal of Alternative & Complementary Medicine 2005; 11 (1):13-20.

■Thompson EA, Reillly D. The homeopathic approach to symptom control in the cancer patient: a prospective observational study. Palliative Medicine. 2002; 16 (3):227-33.
Tiller WA. On chemical medicine, thermodynamics, and homeopathy. J Altern Complement Med 2006; 12 (7):685-93.

■Torres JL. Homeopathic effect: a network perspective. Homeopathy: the Journal of the Faculty of Homeopathy. 2002a; 91 (2):89-94.

■Torres JL. On the physical basis of succussion. Homeopathy 2002b; 91 (4):221-4.

■Torres JL, Ruiz MAG. Stochastic resonance and the homeopathic effect. British Homoeopathic Journal 1996; 85:134-40.

■van Wassenhoven M, Ives G. An observational study of patients receiving homeopathic treatment. Homeopathy 2004; 93 (1):3-11.

■van Wijk R, Bosman S, van Wijk EP. Thermoluminescence in ultra-high dilution research. J Altern Complement Med 2006; 12 (5):437-43.

■Van Wijk R, Wiegant FA. The similia principle as a therapeutic strategy: a research program on stimulation of self-defense in disordered mammalian cells. Alternative Therapies in Health & Medicine. 1997; 3 (2):33-8.

■van Wijk R, Wiegant, F.A.C. Cultured Mammalian Cells in Homeopathy Research. The Similia Principle in Self-Recovery. Utrecht, The Netherlands: Universiteit Utrecht; 1994.

■Vandenbroucke JP. Homeopathy trials: going nowhere. Lancet 1997; 350:824.

■Vickers AJ, Smith C. Homoeopathic Oscillococcinum for preventing and treating influenza and influenza-like syndromes. Cochrane Database Syst Rev 2006; 3:CD001957.

■Weatherley-Jones E, Nicholl JP, Thomas KJ et al. A randomised, controlled triple-blind trial of the efficacy of homeopathic treatment for chronic fatigue syndrome. Journal of Psychosomatic Research 2004a; 56:189-97.

■Weatherley-Jones E, Thompson E, Thomas K. The placebo-controlled trial as a test of complementary and alternative medicine: observations from research experience of individualised homeopathic treatment. Homeopathy. 2004b; 93 (4):186-9.

■Witt C, Keil T, Selim D, Roll S, Vance W, Wegscheider K, Willich SN. Outcome and costs of homoeopathic and conventional treatment strategies: a comparative cohort study in patients with chronic disorders. Complement Ther Med. 2005a; 13 (2):79-86.

■Witt C, Ludtke R, Weisshuhn TE, Willich SN. High homeopathic potencies are different from potentized solvent when investigated with the REDEM technology. Forsch Komplementarmed Klass Naturheilkd. 2005b; 12 (1):6-13.

■Witt CM, Bluth M, Albrecht H, Weisshuhn TE, Baumgartner S, Willich SN. The in vitro evidence for an effect of high homeopathic potencies–a systematic review of the literature. Complement Ther Med. 2007; 15 (2):128-38.

■Witt CM, Ludtke R, Baur R et al. Homeopathic medical practice: long-term results of a cohort study with 3981 patients. BMC Public Health 2005; 5:115.